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Reduced proliferation of bone marrow MSC after allogeneic stem cell transplantation is associated with clinical outcome

Christiane Katzerke,Judith Schaffrath,Jana Lützkendorf,Maike Janssen, Anne-Kathrin Merbach,Katrin Nerger,Mascha Binder, Cornelia Baum, Kirstin Lauer,Christian Rohde,Edith Willscher, Carsten Müller-Tidow,Lutz P. Müller

Blood Advances（2023）

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Abstract
•Allogenic SCT leads to damage of the proliferative capacity of BM-MSC.•This damage correlates with clinical outcome of alloSCT, reduced patient survival, and impaired engraftment of allogeneic hematopoiesis.
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Key words
allogeneic stem cell transplantation,bone marrow msc,stem cell,bone marrow
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