High-mobility group box-1 peptide ameliorates bronchopulmonary dysplasia by suppressing inflammation and fibrosis in a mouse model

Takeya Hara,Takashi Shimbo,Tatsuo Masuda,Tomomi Kitayama,Makoto Fujii, Morifumi Hanawa, Kazuha Yokota,Masayuki Endo,Takuji Tomimatsu,Tadashi Kimura,Katsuto Tamai

Biochemical and Biophysical Research Communications（2023）

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摘要

•Bronchopulmonary dysplasia (BPD) is a chronic lung disorder.•HMGB1 peptide exerts anti-inflammatory and anti-fibrotic effects.•HMGB1 peptide may be used clinically in the treatment of BPD in the future.

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