A Study to Assess the Risk Factors of Thyroid Functions among Bangladeshi Women during 1st Trimester of Pregnancy

Abstract Background: In recent years many researches has centered on the influence of thyroid disease on pregnancy and the consequence of offspring.Aim: The present study was conducted to evaluate the relationship of multiple risk factors and thyroid functions among Bangladeshi young women during 1st half of the pregnancy.Material and methods: This cross-sectional study was done in in the Department of Obstetrics & Gynecology of Dhaka Medical College Hospital, Dhaka on 200 pregnant women in their 1st half of pregnancy attending antenatal clinic, DMCH from December 2018 to December 2019. Where inclusion criteria were healthy singleton pregnant women up to 20 weeks of gestation.Results:According to this study, 10.5% subclinical hypothyroidism group and 36.8% from overt hypothyroidism patients had family history of thyroid dysfunction. 6.5% had stage-1 hypertension and 11% patients had stage-2 hypertension. Also, abnormal blood pressure level is highly correlated with thyroid dysfunction status. The rate of iron disfunction strongly correlated with thyroid dysfunction. 6% patients had mid-level of iron deficiency and 13.5% had iron deficiency anemia. Also, 62.5% had mild hemoglobin level and 37.5% had moderate- severe mild hemoglobin level.Conclusion:The results indicate that, iron deficiency, hypertension can be seen in hypothyroidism during the 1st half of pregnancy. Hence, routine thyroid monitoring, checkup and appropriate management is necessary for hyperthyroidism in the 1st half of pregnancy to avoid more adverse outcome.