Co-Existing Serous Epithelial Ovarian cancer with Hepatocellular Carcinoma: A Rare Case Report

Abstract BackgroundSerous epithelial ovarian cancer co-existing with primary liver cancer is a rare situation, and only few cases have been reported that patients have multiple primary cancers (MPCs) with ovarian cancer.Case presentationWe present the case of a 57-year-old patient whose imaging examination results suggested liver and ovarian lesions. The patients underwent a positron emission computed tomography that revealed the presence of hypermetabolic areas in bilateral adnexal, uterus and pelvic region. After discussion at the multidisciplinary team meeting, the patient underwent surgery and her pathological results were high-grade serous epithelial ovarian cancer and hepatocellular carcinoma (mixed type), respectively. Complete cytoreduction was successfully performed. Her elevated tumor markers like AFP and CA125 decreased immediately after the operation. Now she has received 4 cycles of chemotherapy. The patient showed good tolerance, and showed no sign of recurrence.ConclusionThe present study delineates a rarely reported case of disease with a relatively high incidence rate. Therefore, further studies are required for the perfection of its diagnosis, prevention, and treatment. This case could be a reference for the diagnosis and treatment of ovarian cancer with metastasis of ovarian cancer and other primary tumor.