Chemotherapy outcomes in EGFR-TKI resistant patients with common and uncommon EGFR mutation: An exploratory retrospective cohort study.

Chien-Yu Lin, Chia-Hao Hu, Chia-Fu Hsu,Jeng-Shiuan Tsai,Chian-Wei Chen, Chia-Yin Lin,Chao-Chun Chang,Yi-Ting Yen,Yau-Lin Tseng,Po-Lan Su,Chien-Chung Lin

Thoracic Cancer（2023）

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摘要

This study suggests that patients with uncommon EGFR mutations have poorer chemotherapy responses and shorter survival than those with common EGFR mutations. The development of new treatment strategies for these patients remains an unmet need.

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关键词

chemotherapy,epidermal growth factor receptor,tyrosine kinase inhibitors,uncommon mutation

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