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Integration of ceritinib and bevacizumab as a promising treatment strategy for brain metastases from ALK mutation-position non-small cell lung cancer: a case report

Yinxue Xia, Shuhe Lu,Weixi Shen,Tao Xin,Chengjuan Fan,Chong Teng,Xiaowei Song,Yanju Lv

Authorea (Authorea)（2021）

Cited 0|Views4
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Abstract
Ceritinib shows efficacy in ALK+ NSCLC patients with BM. However, the disease will inevitably progress over time due to acquired resistance. We now report a case with BM from advanced lung adenocarcinoma with ALK mutations who exhibited a surprising and long-term response to treatment of ceritinib combined with bevacizumab.
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Key words
lung cancer,brain metastases,bevacizumab,ceritinib,mutation-position,non-small
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