Understanding the effectiveness of different exercise training programme designs on V?O2peak in COPD: a component network meta-analysis
THORAX(2023)
Abstract
Pulmonary rehabilitation programmes including aerobic training improve cardiorespiratory fitness in patients with COPD, but the optimal programme design is unclear. We used random effects additive component network meta-analysis to investigate the relative effectiveness of different programme components on fitness measured by V?O-2peak in COPD. The included 59 studies involving 2191 participants demonstrated that V?O-2peak increased after aerobic training of at least moderate intensity with the greatest improvement seen following high intensity training. Lower limb aerobic training (SMD 0.56 95% CI 0.32;0.81, intervention arms=86) and the addition of non-invasive ventilation (SMD 0.55 95% CI 0.04;1.06, intervention arms=4) appeared to offer additional benefit but there was limited evidence for effectiveness of other exercise and non-exercise components.
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Key words
exercise training,copd,meta-analysis
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