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Performance of equations for calculated LDL-C in hypertriglyceridaemia: Which one correlates best with directly measured LDL-C?

Clinica Chimica Acta(2023)

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Abstract
•LDL-C predictive equations, especially the Friedewald,are affected by hypertriglyceridaemia.•LDL-C predictive equations are also affected by choice of measurement platform.•Abbott and Roche Cobas direct LDL Cholesterol (d-LDLC) was assessed.•In hypertriglyceridaemia, the e-MH correlates better with dLDL-C than the S-NIH2 equation.
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Key words
Low-density lipoprotein cholesterol equation,Calculated LDL-cholesterol,Friedewald,Sampson,NIH,Extended Martin-Hopkins equation,South Africa
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