Access to polycyclic diazepino[5,6,7-cd]indoles from isatins via tandem 1,5-hydride transfer/cyclization

The method toward diazepino[5,6,7-cd]indoles has been realized via 1,5-hydride transfer/cyclization reaction, using the substituted isatins and diethyl aminomalonate as starting material. This protocol fea-tured redox-neutral conditions and atom-and step-economy.(c) 2023 Elsevier Ltd. All rights reserved.