Recombinant factor IX Fc prophylaxis reduces pain and increases levels of physical activity, with sustained, long-term improvements in patients with hemophilia B: post hoc analysis of phase III trials using patient-reported outcomes.
Therapeutic advances in hematology（2023）
Abstract
rFIXFc prophylaxis reduced perceived pain and increased levels of physical activity with sustained, long-term improvements in QoL in adult and adolescent patients with hemophilia B and maintained high QoL scores in pediatric patients.
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Key words
factor IX,hemophilia B,pain,patient-reported outcome measures,physical activity,quality of life,rFIXFc protein
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