Comparison of two new HTLV-I/II screening methods, Abbott Alinity i rHTLV-I/II and Diasorin LIAISON® XL murex recHTLV-I/II, to Abbott architect rHTLVI/II assay

Vincent Guiraud,Florian Crémoux, Isabelle Leroy, Julien Cohier, Pierre Hernandez, Safietou Mansaly,Agnès Gautheret-Dejean

Journal of Clinical Virology(2023)

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摘要
•HTLV diagnosis requires a serological assay and a Western blot or line immunoassay.•We used ARCHITECT with HTLV BLOT 2.4 for positive samples as the reference assay.•Alinity and Liaison had a total agreement for positive and negative serum samples with the reference.•Alinity and Liaison assays allowed highly discrimination for both positive and negative samples.•Alinity and Liaison assays are suitable for HTLV screening.
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关键词
Human T-cell lymphotropic virus,Serological assay,Method comparison,ARCHITECT rHTLVI/II,Alinity i rHTLV-I/II,LIAISON® XL murex recHTLV-I/II
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