Mature tertiary lymphoid structures are key niches of tumour-specific immune responses in pancreatic ductal adenocarcinomas.

Gabriela Sarti Kinker,Glauco Akelinghton Freire Vitiello, Ariane Barros Diniz,Mariela Pires Cabral-Piccin, Pedro Henrique Barbosa Pereira, Maria Letícia Rodrigues Carvalho,Wallax Augusto Silva Ferreira,Alexandre Silva Chaves,Amanda Rondinelli, Arianne Fagotti Gusmão,Alexandre Defelicibus,Gabriel Oliveira Dos Santos,Warley Abreu Nunes,Laura Carolina López Claro, Talita Magalhães Bernardo,Ricardo Tadashi Nishio,Adhemar Monteiro Pacheco,Ana Carolina Laus,Lidia Maria Rebolho Batista Arantes,Julia Lima Fleck,Victor Hugo Fonseca de Jesus,André de Moricz, Ricardo Weinlich,Felipe José Fernandez Coimbra,Vladmir Cláudio Cordeiro de Lima,Tiago da Silva Medina

Gut（2023）

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Abstract

We provided a framework for understanding the biological role of PDAC-associated TLSs and revealed their potential to guide the selection of patients for future immunotherapy trials.

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Key words

IMMUNE RESPONSE, PANCREATIC CANCER

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