Topology optimization for fluid flow devices modeled through the Multiple Reference Frame approach

•Topology optimization formulation for designing fluid flow devices through the Multiple Reference Frame approach.•Adjustments in the Topology Optimization of Binary Structures approach for the Multiple Reference Frame approach.•New combination for the multi-objective function is proposed for impeller-diffuser topology optimization.•Method for the conceptual design of predominantly radial impeller-diffuser of centrifugal pumps is presented.