Metal-Free Oxidative Cross-Dehydrogenative Coupling of Alkenes with Thiophenols

A novel transition-metal-free regioselective allylic C-H thiolation of alkenes has been achieved by cross-dehydrogenative coupling strategy. The present protocol realizes efficient and highly regio- and stereo-selective functionalization of allylic C-H bonds under metal-free conditions, leading to a series of allylic thioethers in good to excellent yields. Moreover, this work features mild reaction conditions, high step- and atom-economy and good functional group tolerance.