Large-scale analysis of putative plasmids in clinical multidrug-resistant Escherichia coli isolates from Vietnamese patients.

Quang Huy Nguyen,Thi Thu Hang Le,Son Thai Nguyen, Kieu-Oanh Thi Nguyen,Dong Van Quyen,Juliette Hayer,Anne-Laure Bañuls, Tam Thi Thanh Tran

Frontiers in microbiology（2023）

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摘要

Our study provides evidence of horizontal gene transfer in multidrug-resistant isolates via conjugative plasmids, thus rapidly accelerating the emergence of resistant bacteria. Besides reducing antibiotic misuse, prevention of plasmid transmission also is essential to limit antibiotic resistance.

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关键词

Escherichia coli,putative plasmid,carbapenem resistance,horizontal gene transfer,whole-genome sequencing

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