TERT Mutations in Non-Small Cell Lung Cancer: Clinicopathologic Features and Prognostic Implications.

CLINICAL MEDICINE INSIGHTS-ONCOLOGY(2023)

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摘要
mutations were present in 11% of patients with NSCLC. mutations were associated with age, smoking history, sex, and distant metastasis. Co-mutations in and indicated a poor prognosis. The co-mutations of and differed according to sex, histopathology type, and metastasis, whereas and co-mutations were only associated with patient metastasis. Age, cancer stage, and mutation carrier status were independent risk factors for poor prognosis in patients with NSCLC.
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关键词
Non-small cell lung cancer,TERT,co-mutation,prognosis
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