Evaluating the expression of microRNA-15a-5p and YAP1 gene in oral squamous cell carcinoma in comparison with normal tissue: A cross-sectional study.

Padmavathi Saravana Murthy,A Kannan,Anuradha Ganesan,Krithika Chandrasekar Lakshmi, Yesoda Aniyan Kumbalaparambil

JOURNAL OF ORAL PATHOLOGY & MEDICINE（2023）

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摘要

In conclusion, this study demonstrated that miRNA-15a-5p was downregulated and YAP1 was overexpressed, which had a statistically significant difference between the normal and OSCC groups. Therefore, miRNA-15a-5p may serve as a novel biomarker to better understand the pathology and as a potential target in OSCC therapy.

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关键词

microRNA,miRNA-15a-5p,oral cancer,oral squamous cell carcinoma,YAP1

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