Utilization of Silanols in Transition Metal-Catalyzed Organic Synthesis

The multifaceted implementation of silanols in organicsynthesisis reviewed from the standpoint of developments in transition metal-catalyzedreactions. The major properties of silanols are summarized accordingto the research fields that have utilized these intriguing species:silanols as nucleophiles to serve as bulky surrogates for water; silanolsas temporary ligands to control regioselectivity of metal-catalyzedreactions; silanols as coupling partners for transferring functionalgroups. These topics are summarized to provide opportunities for futuredevelopments in the chemistry of silanols.