ARCHE-NOAH: NMR supersequence with five different CEST experiments for studying protein conformational dynamics

An NMR NOAH-supersequence is presented consisting of five CEST experiments for studying protein backbone and side-chain dynamics by N-15-CEST, carbonyl-(CO)-C-13-CEST, aromatic-C-13(ar)-CEST, C-13(alpha)-CEST, and methyl-C-13(met)-CEST. The new sequence acquires the data for these experiments in a fraction of the time required for the individual experiments, saving over four days of NMR time per sample.