N-acetyl cysteine: A new look at its effect on PTZ-induced convulsions.

Cansu Bilister Egilmez,Burcu Azak Pazarlar,Mumin Alper Erdogan,Oytun Erbas

Epilepsy research（2023）

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摘要

We can report that 300 mg/kg and 600 mg/kg doses of NAC are promising with their reducing effect on convulsions and have a beneficial effect by preventing oxidative stress. In addition, NAC has been also determined that this effect is dose-dependent. Detailed and comparative studies are needed on the convulsion-reducing effect of NAC in epilepsy.

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关键词

N-acetyl cysteine,Epilepsy,Pentylenetetrazol,Anticonvulsant,Oxidative stress

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