Hemorheological models applied to data analysis in groups of patients and in healthy subjects

JOURNAL OF MECHANICS IN MEDICINE AND BIOLOGY(2023)

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摘要
An overview of some mathematical models describing the rheological behavior of blood is done. Several known models were used to describe the non-Newtonian rheological properties of blood. The parameters of two of the simplest models - the power law and the Herschel-Bulkley law were used to analyze the differences between the microrheological and micromechanical characteristics of blood in a group of patients with diabetes mellitus type 2 (T2DM) and in healthy subjects. The experiments were carried out with Low Shear 30 (LS 30) Contraves viscometer in a wide range of shear rates. All experimental data were statistically processed using the Mann-Whitney U-test for intergroup comparison of independent variables, as well as the t-test. The Statistica program was used for statistical processing. The results obtained are compared with the hemorheological models from other disease states.
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关键词
Hemorheology, mathematical modeling overview, constitutive equations, diabetes mellitus type 2 (T2DM)
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