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Correlations between kynurenines in plasma and CSF, and their relation to markers of Alzheimer’s disease pathology

Brain, Behavior, and Immunity(2023)

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摘要
•Plasma levels of all kynurenines were positively correlated with those in CSF.•Correlations between plasma and CSF were strongest for QA.•QA showed a tendency for positive associations with CSF Aβ1-42.•KYN, KA, and KTR in CSF were all positively associated with CSF Aβ1-42.•KYN, both in plasma and CSF, was negatively associated with CSF p-tau.
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关键词
kynurenines,alzheimers
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