IL-38 attenuates myocardial ischemia-reperfusion injury by inhibiting macrophage inflammation.
Immunity, inflammation and disease（2023）
Abstract
IL-38 attenuates MIRI by inhibiting macrophage inflammation. This inhibitory effect may be partially achieved by inhibiting the activation of NOD-like receptor pyrin domain-related protein 3 inflammasome, resulting in decreased expression of inflammatory factors and reduced cardiomyocyte apoptosis.
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Key words
interleukin-38,macrophages,myocardial apoptosis,myocardial ischemia-reperfusion injury
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