Effects of tetramethylpyrazine on platelet function in tumor patients with chemotherapy

Objective To study the effects of tetramethylpyrazine(TMP)on platelet function and the relationship with chemotherapy of tumor patients.To prove that activating blood and resolving stasis for chemotherapy's impact is efficient.Methods 180 patientswith tumorwere divided equally into treatment group(90 cases)and control group(90 cases)on random.The treatment group was synchronously received chemotherapy and TMP(80 mg/d,1/d,Injection);the control groupwas only using chemotherapy.To compare the platelet index difference,effective rate of treatment(RR),and benefit rate between the two groups.Results The clinical benefit rate was 82.2% in treatment group,and 75.61% in control group.The effective rate was 57.78% in treatment group,and 51.22% in control group(P 0.05).The differences both had statistical significance.Afterthe treatmentthe plateletindexhad significantimprovement,and treatmentgroupwas superior to control group(P 0.05).Conclusion The hypercoagulable state of tumor patients in treatment group had significant improvement.The TMP combined with chemotherapy could heighten the curative effect of chemotherapy.