Resistance exercise counteracts the impact of androgen deprivation therapy on muscle characteristics in cancer patients.

Maarten Overkamp,Lisanne H P Houben,Thorben Aussieker,Janneau M X van Kranenburg,Philippe J M Pinckaers,Ulla R Mikkelsen,Milou Beelen,Sandra Beijer,Luc J C van Loon,Tim Snijders

The Journal of clinical endocrinology and metabolism（2023）

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摘要

The onset of ADT is followed by a decline in both type I and type II muscle fiber size and capillarization in PCa patients. Resistance exercise training offsets the negative impact of androgen deprivation therapy and increases type I and II muscle fiber size and type I muscle fiber capillarization in these patients.

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关键词

skeletal muscle,angiogenesis,testosterone,older adults,exercise rehabilitation

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