Preliminary transcriptomic analysis of peripheral blood from German Shepherd dogs with degenerative joint disease for the identification of diagnostic biomarkers.

Gisel Padula,Gabriela Rudd Garces,María Elena Fernández, Rosario Vercellini, Daniel Osvaldo Arias,Pilar Peral García,Guillermo Giovambattista

Gene（2023）

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摘要

The gene-encoding protein THBS4 is correlated with DJD severity and long noncoding RNA LOC106559235 is probably involved in the DJD process. The THBS4 gene should be considered a good biomarker for DJD in dogs. Future studies using independent cohorts will be necessary to validate the present results.

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关键词

Canis lupus familiaris,RNA-seq,Differential gene expression,DJD,Precision medicine

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