The Correlation between NPS and Polysubstance Use in High-Risk Population: a Five-year Longitudinal Study in Taiwan
INTERNATIONAL JOURNAL OF MENTAL HEALTH AND ADDICTION(2023)
摘要
The emergence of new synthetic substances (NPS) leads to rapid changes in substance prevalence. Here urine analysis and questionnaires were employed to construct a landscape of substance abuse. 3,064 urine samples were randomly selected from suspected substance abusers (N = 6,335) from 2014 to 2018 in Taiwan. Demographic information was self-reported. Principal component analysis (PCA) were used to explore the substance pattern. The positive detection of NPS reached 19.6%. The highest links of polysubstance use were the use of phenethylamines with the co-use of amphetamines (aOR = 4.33), benzodiazepines (aOR = 2.09), and synthetic cathinones (aOR = 5.01) and the use of synthetic cathinones with the co-use of ketamine (aOR = 6.72) and benzodiazepines (aOR = 2.62). No evidence indicating an increase in the use of NPS/other substances as a replacement for traditional substances. The presence of polysubstance patterns may be due to similarities in the effects of the various substances or users undergoing a transition in their substance abuse patterns.
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关键词
NPS,Polysubstance use,High risk population,Urinalysis,Demographic factors
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