Long-read Sequencing and de novo Genome Assembly of Three Aspergillus fumigatus Genomes
Mycopathologia(2023)
摘要
Aspergillus fumigatus is a genetically diverse fungal species, which is near ubiquitous in its global distribution and is the major cause of the life-threatening disease invasive aspergillosis. We present 3 de novo genome assemblies that were selected to be representative of the genetic diversity of clinical and environmental A. fumigatus . Sequencing using long-read Oxford Nanopore and subsequent assembly of the genomes yielded 10–23 contigs with an N50 of 4.05 Mbp to 4.93 Mbp.
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关键词
Aspergillus fumigatus,Oxford nanopore sequencing,de novo genome assembly,Fungal genome,Azole resistance
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