Dynamic Change of Lumbar Structure was Associated with Reduced Bone Mineral Density, a Clinical Retrospective Study

Abstract Objectives: This study aims to determine whether the dynamic change of lumbar anatomy parameters is associated with bone mineral density.Methods: This retrospective study included participants who did lumbar computed tomography (CT) scanning from October 2018 to December 2021. The established and recorded CT scanning images were used for analysis. Bone mineral density (BMD) was determined by the qCT value. CT scanning was also used to measure angle between upper and lower endplate on median sagittal view, and that between pedicle center and horizontal alignment on median sagittal view and transverse section angle on the axial view. Results: 476 participants were included. Angle between upper and lower endplate on median sagittal view in lumbar 1 (5.72±3.60), lumbar 2 (4.03±3.14), lumbar 3 (2.60 ±3.08) was positively associated with BMD, while that in lumbar 4 (2.07±4.66) was negatively associated (All P<0.05). Furthermore, angle between pedicle center and horizontal alignment on median sagittal view in lumbar 1 (-1.89±6.49), lumbar 2 (-2.10±6.96), and lumbar 3 (-0.75±5.61) was positively associated with BMD (P<0.001 for them all). However, this angle in lumbar 4 (2.99±4.78) showed no correlation with BMD (P=0.961). However, no significant correlation was observed between transverse section angle on the axial view and BMD. Conclusion: The dynamic change of lumbar anatomy parameters is associated with BMD and thus orthopadic surgeons should pay attention to these changes in the internal fixation operation.