Effect of miR-196a2 rs11614913 polymorphism on cancer susceptibility: evidence from an updated meta-analysis

Review question / Objective: MiR-196a2 rs11614913 polymorphism has been studied in a wide range of cancers throughout the years. Despite a large number of epidemiological studies performed in almost all ethnic populations, the contribution of this polymorphism in cancer risk is still inconclusive. Therefore, this updated meta-analysis was performed to estimate a meticulous correlation between miR-196a2 rs11614913 variant and cancer susceptibility. Condition being studied: Different types of cancer patients and healthy controls were evaluated to detect the cancer risk in the individual case-control studies. We performed a meta analysis of these case control studies to get a pulled outcome risk.