SARS-CoV-2 neutralizing antibodies in Chile after a vaccination campaign with five different schemes

Ximena Aguilera,Juan Hormazabal,Cecilia Vial,Lina Jimena Cortes,Claudia Gonzalez,Paola Rubilar,Mauricio Apablaza,Muriel Ramirez-Santana,Gloria Icaza,Loreto Nuñez-Franz,Carla Castillo-Laborde,Carolina Ramirez-Riffo,Claudia Perez,Ruben Quezada-Gate, Macarena Said,Pablo Vial

medRxiv (Cold Spring Harbor Laboratory)（2022）

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摘要

AbstractUsing levels of neutralizing antibodies (nAbs), we evaluate the successful Chilean SARS-CoV-2 vaccine campaign, which combines technologies and heterologous boosters. In 120 randomly selected seropositive individuals from a population-based study, we conclude that the booster dose, regardless of vaccine technology or natural infection, and mRNA vaccines significantly improve nAbs response.

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关键词

vaccination campaign,antibodies,chile,sars-cov

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