Therapy of advanced head and neck cancer with double checkpoint blockade followed by radioimmunotherapy – results of the CheckRad-CD8 study.

Antoniu-Oreste Gostian, Markus Eckstein,Sandra Rutzner,Jens von der Grün,Thomas Illmer,Matthias G. Hautmann,Thomas B. Brunner,Simon Laban,Gunther Klautke,Balint Tamaskovics,Benjamin Frey,Arndt Hartmann,Wilfried Budach,Udo Gaipl,Heinrich Iro,Rainer Fietkau,Markus Hecht

Laryngo-rhino-otologie（2022）

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摘要

Introduction The CheckRad-CD8 study investigates the feasibility and efficacy of chemo-immune induction therapy followed by radioimmunotherapy with double immune checkpoint blockade after prior patient selection based on intratumoral CD8 cells.

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关键词

neck cancer,radioimmunotherapy,double checkpoint blockade

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