Hyperoside: a review of pharmacological effects
F1000Research(2022)
Abstract
Hyperoside, also known as quercetin-3-O-β-D-galactopyranoside, belongs to the class of flavonol glycosides. Its aglycon is quercetin, and the sugar base is galactopyranoside. It is made of quercetin. The O atom at the 3rd position of the element is connected to the sugar group by a β-glycosidic bond. Hyperoside, which is widely present in the planted objects, such as the fruits and whole plants of Hypericaceae, Rosaceae, Campanulaceae, Lamiaceae, and Berberis spp., has received extensive attention due to its anti-inflammation, anti-oxidation, anti-tumor, and other disease activities, as well as its protective effects on the cardiovascular system, nervous system, digestive system and immune system. While glycosides are a commonly researched topic, there are very few studies on the metabolic pathways, and its overuse and adverse reactions are rarely reported. This article provides a comprehensive review of the pharmacological research results of hyperoside, and a new perspective on the limitations of the existing research on metabolic pathways and toxicology. It provides new ideas for further research and clinical application of hyperoside.
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Key words
pharmacological effects
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