AB0755 Hip denervation and intra-articular hydration in axial spondyloarthritis patients with hip damage
Annals of the Rheumatic Diseases(2022)
Abstract
BackgroundThe hip joint is frequently affected in axial spondyloarhritis (SpA) of the adults with destructive effect in untreated patients. About 35% of axial SpA patients had either unilateral or bilateral hip arthritis. Destruction is more common with early-onset, active disease, or enthesitis [1, 2].ObjectivesThe aim of this study is to evaluate the effect of hip denervation (HD) and intra-articular hydration (IAH) on pain, function score, hip mobility scores in a cohort of axial SpA patients with grade 3 and 4 hip BASRI score.MethodsWe enrolled 40 patients who fulfilled ASAS criteria for axial SpA. All had hip involvement with grade 3 or 4 BASRI score at baseline.They were divided into 4 groups; group one received placebo, group 2 HD, group 3 IAH, and group 4 received HD and IAH. They all were assessed at baseline and after 4 weeks and 12 weeks. Outcome measures included; VAS, semi-quantitative scores of tenderness for the hip, range of motion, and Harris functional hip score (HHS).ResultsA significant improvement of VAS pain, tenderness score, ROM, HHS were detected in group 4 versus other groups (p < 0.05). Group 2 had significantly lower scores of tenderness and pain compared to group 3 (p < 0.05). In contrast, the patients of group 3 show better ROM and HHS than the patients of group 2 (p < 0.05). At 4- and 12-week, all therapeutic groups (2, 3, and 4) show considerable improvement in comparison to placebo (group 1) (p < 0.05).ConclusionHD and IAH can improve pain and function in damaged hip of axial SpA patients, especially when concurrently used.References[1]Han, Q., et al., A Comprehensive Assessment of Hip Damage in Ankylosing Spondylitis, Especially Early Features. Frontiers in Immunology, 2021. 12: p. 880.[2]Elsaman, A., A. Hamed, and A. Radwan, Ultrasound-guided epidural block in axial spondyloarthritis patients with limited spine mobility: a randomized controlled trial. The Korean journal of pain, 2021. 34(1): p. 114.Disclosure of InterestsNone declared
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