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Silica nanoparticles induce hepatocyte ferroptosis and liver injury via ferritinophagy

Qingqing Liang,Yuexiao Ma,Fenghong Wang,Mengqi Sun,Lisen Lin,Tianyu Li,Zhiwei Sun,Junchao Duan

Environmental Science: Nano（2022）

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Abstract
Short-term SiNPs exposure activated ferritinophagy in hepatocytes, which was responsible for subsequent ferroptosis and ultimately liver injury.
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Key words
hepatocyte ferroptosis,liver injury,nanoparticles,silica
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