Case Report of Oral Temozolomide Therapy by Total Gastrectomy Patient

Noriko Sakata, Hiroaki Mastuoka,Takaaki Kodawara,Takashi Higashi,Ryoichi Yano,Kyohei Watanabe,Hitoshi Tsukamoto,Yoshifumi Higashino,Takahiro Yamauchi,Ryuhei Kitai,Kenichiro Kikuta,Nobuyuki Goto

Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences)（2021）

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Abstract

We experienced oral temozolomide treatment for total gastrectomy in a high-grade glioma patient. In this case, as there was concern about hydrolysis of temozolomide due to total gastrectomy, we measured the temozolomide concentration during the treatment period. Furthermore, the side effects of 18 non-total gastrectomy patients who had been treated with oral temozolomide therapy in the past were evaluated and compared with the side effects of this gastrectomy patient.

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Key words

oral temozolomide therapy,total gastrectomy patient,case report

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