Epigenetic drugs based on antiaging approach: an overview

Elsevier eBooks(2022)

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摘要
Aging is a natural physiological process that takes place during the course of life in all living beings. It is the main culprit in the growth and development of several chronic diseases because of changes or gradual decline of normal physiological functions. Several reports revealed that the epigenetic changes foisted and established a great impact on the aging process. Indeed, aging associated with epigenetic dysregulations imposes serious health concerns for various human pathologies including metabolic diseases, cardiovascular diseases, cancer, neurological and psychological disorders. During the last few decades, a variety of natural and synthetic drugs are being employed for various therapeutic applications because of antiaging attributes; however, the results are still unsatisfactory. Therefore, nowadays, epigenetic drugs-based therapy has emerged as a possible and crucial approach for the treatment of several diseases associated with aging. In a nutshell, this chapter epitomes the role of epigenetic drugs that not only targets epigenetic pathways involved in a myriad of pathologies but also improves the lifespan of patients.
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epigenetic drugs
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