Efficacy of sonic activation techniques on tubular dentin sealer penetration：A systematic review and meta-analysis

Review question / Objective: Is sonic activation techniques more effective than conventional needle irrigation for the tubular dentin sealer penetration. The included study was a randomized controlled trial. Eligibility criteria: A comprehensive search was conducted for all published studies evaluating efficacy of percentage and maximum depth of sealer penetration, following the use of SI and standardized irrigants (NaOCl and EDTA). Because this can hardly be measured clinically, only confocal laser scanning microscopy (CLSM) studies were selected owing to wide use of this methodology for evaluating tubular dentin sealer penetration. The studies using previously filled roots or animal teeth, artificial debris, and plastic blocks, and studies measuring the penetration of tubular dentin sealers in lateral root canals, isthmus, or artificial grooves were excluded to maintain the standardized sample selecting and measuring (Virdee et al. 2018). The search was limited to articles published between January 2000 and June 2022 to ensure conclusions were drawn from contemporary data. There are no language restrictions on filtering articles to ensure the integrity of included data.