Neuroprotective Effect of Sub-lethal Hyperthermia Preconditioning in a Rat Model of Repeated Closed Head Injury
Neuroscience(2023)
摘要
•Hyperthermia preconditioning improves locomotor activity and anxiety-like behavior.•Hyperthermia preconditioning improves recognition and spatial memory.•Hyperthermia preconditioning inhibits rCHI-induced neuronal loss, injury, and apoptosis.•Hyperthermia preconditioning suppresses rCHI-induced excessive glial cells activation.
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关键词
sub-lethal hyperthermia,repeated closed head injury,heat shock protein,neuroprotection,neuroinflammation
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