外周T细胞淋巴瘤基因改变及分子分型研究进展

Journal of Leukemia and Lymphoma(2023)

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Abstract
外周T细胞淋巴瘤(PTCL)是一组异质性强、预后差的恶性肿瘤,缺乏标准的治疗方案且传统化疗疗效欠佳,因此寻找新的、更有效的治疗靶点以提高PTCL的疗效是临床亟待解决的问题。近来随着对PTCL基因及分子层面探索的深入,发现了基于基因改变和分子分型的新型治疗靶点。文章总结了近年来PTCL主要的基因改变及分子分型研究进展。
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Key words
Peripheral T-cell lymphoma,Gene alteration,Molecular typing,Molecular targeted therapy
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