Effect of hyperthyroidism treatments on heart rate variability: A systematic review and meta-analysis

Review question / Objective: The reversibility of HRV abnormalities in hyperthyroidism remains contradictory. The purpose of the study is to conduct a systematic review and meta-analysis on the effect of antithyroid treatments on HRV in hyperthyroidism. Population: Untreated hyperthyroid patients Intervention: Antithyroid treatment Control: Controls without hyperthyroidism Outcomes: Reversibility of heart rate variability abnormalities in hyperthyroidism Study design: Systematic review. Information sources: All studies that addressed the effect of hyperthyroidism treatment on HRV were reviewed. Studies were searched electronically through the major article databases (PubMed, Cochrane Library, Embase, and Google Scholar) with the following keywords: ("hyperthyroidism" OR "hyperthyroid") AND ("heart rate variability" OR "HRV") until April 4, 2022.