A systematic review and meta-analysis on the application of three-dimensional reconstruction in partial nephrectomy

Abstract Objective Three dimensional (3D) reconstruction is widely used in complicated renal surgery. This article focus on investigating the role of three-dimensional reconstruction participated in partial nephrectomy (PN) from a systematic review and meta-analysis. Methods We searched published studies that reported the relationship between 3D reconstruction and PN using PubMed and Embase up to December 8, 2022. STATA version 12.0was used to conduct all analyses. Results Seventeen studies were finally progressed to data extraction. Meta-analysis indicated a significant reduction in operation time ([SMD] =-0.34; confidence interval [CI]: -0.59 to -0.09), global ischemia time ([SMD] =-0.42; CI: -0.64 to -0.21) and opening collecting system rate (OR 0.26, 95% CI 0.14 to0.47).There are no statistically significant differences between 3d reconstruction assisted PN and 2D control group considering estimated blood loss, GFR change, positive surgical margin, length of hospital stay, and intraoperative complication. Conclusion Our study provides evidence that 3D reconstruction played an important role in PN, especially for complex renal tumors. However, more high-quality, larger sample size and more rigorously designed randomized controlled trials which report this topic are still needed to support our conclusions.