Interrelation between the lipid accumulation product index and diabetic kidney disease in patients with type 2 diabetes mellitus

Abstract Aims: The purpose of this study was to determine the relation between the lipid accumulation product index (LAPI) and diabetic kidney disease (DKD) in patients with type 2 diabetes mellitus (T2DM). Methods: Herein, 931 patients were enrolled and their data were collected. Then the interrelation between LAPI and DKD was assessed using multivariate logistic regression analyses (LRAs) and by a restricted cubic spline (RCS). Receiver operating characteristic (ROC) curves were plotted to compare the performance of discrepant indicators of abdominal obesity (AO) in predicting DKD. Results: After adjusting for several confounders, the odds ratio for DKD was increased evidently in the third LAPI tertile compared with that in the first LAPI tertile. In addition, the RCS revealed a positive interrelationbetween LAPI and DKD. As illustrated by ROC curves, LAPI showed better performance in predicting DKD than the other indicators. Conclusions: LAPI is positively linked with DKD, so LAPI may be a suitable indicator for clinically screening patients at risk of DKD.