Paper-Based Computational Multi-Peptide Optical Sensor for Point-of-Care Testing of Lyme Disease

Hyou-Arm Joung,Rajesh Ghosh, Artem Goncharov, Kevin Ngo, Barath Palanisamy, Marcell Veszpremi,Elizabeth J. Horn,Paul M. Arnaboldi,Raymond J. Dattwyler,Omai B. Garner,Dino Di Carlo,Aydogan Ozcan

Frontiers in Optics + Laser Science 2022 (FIO, LS)（2022）

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摘要

We report a paper-based multi-peptide optical sensor processed by a neural network for point-of-care testing of Lyme disease. Using clinical serum samples, we demonstrate 91.7% sensitivity and 100% specificity without cross-reactivity with other diseases.

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关键词

lyme disease,optical sensor,paper-based,multi-peptide,point-of-care

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