Ps-p04-4: blood pressure variability in preschool children

Objective: To investigate the blood pressure variability (BPV) and its relevant factors in preschool children. Design and method: A total of 497 preschool children from two public kindergartens in Shanghai were enrolled. Blood pressure (BP) was standardized measured three times consecutively in a sitting position. Demographic information was collected. The measures used for BPV were the difference between the third and the first systolic blood pressure (SBP) (Delta-SBP), the difference between the third and the first diastolic blood pressure (DBP) (Delta-DBP), standard deviation of SBP (SBPSD) and DBP (DBPSD), and coefficient of variation of SBP (SBPCV) and DBP (DBPCV). Statistical analysis was performed by SAS9.4. Results: The subjects were on average 4.5 ± 0.8 years and 49.7% male. Mean blood pressure was 96/56mmHg. BPV was not significantly different between sex, however, it was significantly different among different SBP grade groups. According to the quartile of the first SBP, the subjects were divided into four groups. SBPSD and SBPCV were greater with the increase in SBP level. DBPSD and DBPCV were not significantly different among groups. Multiple linear regression showed that Delta-SBP was negatively correlated with the first SBP (Fig. 1), that was, the higher the first SBP, the magnitude of decrease from the third SBP to the first SBP was greater. After adjustment for sex, age, height, and weight, the first SBP was positively correlated with SBPCV. Conclusions: This study revealed that the higher the first SBP in preschool children, the greater the blood pressure variability may be.