Scansys Versus Pentacam HR: Evaluating the Possible Interchangeability in Healthy Subjects

Abstract Purpose To determine the interchangeability of Scansys (MediWorks, Shanghai, China) and Pentacam HR (Oculus, Wetzlar, Germany) in healthy participants. Methods Eighty-nine eyes of 45 normal individuals underwent three consecutive scans of Scansys and Pentacam HR. Anterior segment measurements included anterior and posterior K-reading, central corneal thickness (CCT), thinnest corneal thickness (TCT), pupil center pachymetry, corneal volume, chamber volume, anterior chamber depth (ACD), anterior chamber angle (ACA), intraocular pressure (IOP), sphericity (Q-value), pupil diameter, and horizontal white-to-white (HWTW). Infraclass correlations (ICC) for reliability and Bland-Altman plots for the agreement between the mean findings of each device were analyzed. Results The mean age of participants was 31.5 ± 7.3 (range, 19–49) years (male/female = 21/24). Most anterior segment parameters had excellent or good reliability in ICC analysis. However, ACA and HWTW were two parameters with moderate reliability. Analysis of Bland-Altman plots showed that the bias line for all measurements was close to zero, except for posterior flat-k and steep-k readings; however, the discrepancy was not large enough to be clinically important. Analysis of the limit of agreement in Bland-Altman plots also displayed narrow limits and clinically irrelevant differences in 95% LoA for anterior and posterior keratometry readings, CCT, TCT, and ACD. Conclusion The findings provided by this study highlight that Scansys and Pentacam HR can be used interchangeably for anterior segment evaluation regarding most of the examined parameters.