Rationally Designed Minimal Bioactive Domains of AS-48 Bacteriocin Homologs Possess Potent Antileishmanial Properties

Hannah N. Corman,Jessica N. Ross,Francisco R. Fields,Douglas A. Shoue,Mary Ann McDowell,Shaun W. Lee

Microbiology Spectrum（2022）

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摘要

Leishmaniasis is a neglected tropical disease caused by protozoan parasites of the genus Leishmania . There are three primary clinical forms, cutaneous, mucocutaneous, and visceral, with visceral leishmaniasis being fatal if left untreated.

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minimal bioactive domains

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