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Overexpressions of RHOA, CSNK1A1, DVL2, FZD8, and LRP5 genes enhance gastric cancer development in the presence of Helicobacter pylori

Ufuk Demirci,Seda Orenay-Boyacioglu,Elmas Kasap,Emre Gerçeker,Fahri Bilgiç,Hakan Yüceyar,Hatice Yildirim,Ahmed Ramiz Baykan,Ender Berat Ellidokuz,Mehmet Korkmaz

Arab Journal of Gastroenterology（2023）

Cited 1|Views11
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Abstract
Overexpression of RHOA, CSNK1A1, DVL2, FZD8 and LRP5 genes in IM may suggest that these genes are important markers in the development of IM and inflammation with HP. In addition, these genes are linked to tumor burden in the GC group. Consequently, we can conclude that these genes are poor prognosis biomarkers for GC and have the potential to be used as markers for future treatment monitoring.
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Key words
gastric cancer development,gastric cancer,lrp5 genes
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