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Front Cover: Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase‐1 (ChemPhysChem 3/2023)

Sodiq O. Waheed, Ann Varghese, Isabella DiCastri, Brenden Kaski, Ciara LaRouche, Gregg B. Fields, Tatyana G. Karabencheva‐Christova

ChemPhysChem(2023)

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Abstract
The Front Cover show the initially formed and the catalytically productive conformations of MMP-1 complex with the Triple Helical Peptide (THP), the free energy profile connecting them as well as the coordination geometry of the catalytic zinc (II). The background shows the collagen macromolecule. More information can be found in the Research Article by Tatyana G. Karabencheva-Christova and co-workers.
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Key words
collagenolysis,early catalytic events,chemphyschem
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