Epidemiology of breast cancer in the Krasnoyarsk region

AIMS: To assess the epidemiological indicators and the state of oncological care for patients with breast cancer in the Krasnoyarsk Territory from 2011 to 2021. MATERIALS AND METHODS: The study presents an analysis of data in the Krasnoyarsk Territory from 2011 to 2021. Data processing was carried out using Microsoft Excel and Statistica 6.0 software products. The correlation between morbidity and mortality was assessed using Spearmans correlation analysis, and the result was considered statistically significant at a significance level of p 0.05. RESULTS: An analysis of the incidence of breast cancer in the Krasnoyarsk Territory from 2011 to 2021 showed an increase in the number of cases by 35.2%. The peak incidence falls on the age range of 5569 years. The mortality rate for the study period tends to decrease; 1-year mortality decreased from 9.3% to 5.1%. The level of early diagnosis increased to 76.4%, while the rate of advanced forms of breast cancer decreased from 33.5% to 23.6%. There is an increase in the number of patients with breast cancer, registered in the dispensary for 5 years or more, from 54.7% to 62.7%, due to the use of modern clinical recommendations, the use of long courses of adjuvant endocrine therapy (up to 10 years), a wide range and frequency of use of antitumor, including targeted drugs. Correlation analysis between morbidity and mortality rates for the Krasnoyarsk Territory revealed an average, moderate relationship the correlation coefficient (r=0.59; p 0.05). A direct average correlation was obtained between the proportion of newly diagnosed cases of breast cancer at stages III and IV and the 1-year mortality rate (r=0.64; p 0.05). A very strong relationship was found between newly diagnosed cases of breast cancer and diseases detected at early stages (r=0.97; p 0.05). CONCLUSION: The results obtained indicate the effectiveness of ongoing measures for the prevention and early detection of diseases.